Which chemical peel works best for acne? What 12 trials found

What question did the researchers ask?

The review compared common chemical peels for mild-to-moderate acne, including salicylic, glycolic, trichloroacetic, pyruvic and combination approaches.

What did they actually find?

Many head-to-head comparisons found similar improvement. Some individual comparisons favoured a combined salicylic/mandelic peel or glycolic acid over placebo, and treatments were generally well tolerated.

What should you keep in mind?

Study quality ranged from very low to moderate and the protocols were too different for a robust overall pooled conclusion. Peel selection still depends on acne type, skin tone, sensitivity, preparation and the intended depth.

What does this mean for a Highfield consultation?

This review concerns acne; peel type, concentration, skin type and the treatment goal affect relevance. We consider that finding alongside independent guidance, your medical history, examination and priorities. It can support a better-informed decision, but it cannot promise a personal result or decide whether treatment is suitable.