Fractional CO₂ laser for acne scars: what a meta-analysis found

What question did the researchers ask?

The analysis compared fractional CO₂ laser with non-CO₂ laser approaches for acne scars, using clinical improvement, patient and observer ratings, and post-inflammatory hyperpigmentation as outcomes.

What did they actually find?

Across the eight studies, the pooled analysis did not find a significant difference between fractional CO₂ and the comparator laser treatments for the main improvement or satisfaction measures.

What should you keep in mind?

This paper is specific to acne scars and compares laser families rather than proving benefit for every CO₂ indication. Scar type, skin type, energy settings, downtime and pigmentation risk remain important individual factors.

What does this mean for a Highfield consultation?

This evidence concerns acne scarring; other indications need their own assessment and evidence discussion. We consider that finding alongside independent guidance, your medical history, examination and priorities. It can support a better-informed decision, but it cannot promise a personal result or decide whether treatment is suitable.