Does PRP rejuvenate facial skin? What an umbrella review found

What question did the researchers ask?

This review-of-reviews traced 13 systematic reviews back to 28 individual studies of PRP for facial rejuvenation. Most primary studies were uncontrolled and some combined PRP with laser, fat grafting or other injectables.

What did they actually find?

One pooled analysis suggested higher satisfaction when PRP was added to another treatment. Some reviews described improved elasticity or reduced redness with PRP plus laser.

What should you keep in mind?

Certainty was low or very low, methods varied, and adverse events were predefined in only two reviews. The authors concluded that the evidence was insufficient for firm claims about PRP alone or in combination.

What does this mean for a Highfield consultation?

The certainty of evidence was low or very low, with substantial variation between PRP methods. We consider that finding alongside independent guidance, your medical history, examination and priorities. It can support a better-informed decision, but it cannot promise a personal result or decide whether treatment is suitable.